AICAR

Description

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a nucleotide analog and potent AMP-activated protein kinase (AMPK) agonist that plays a critical role in cellular energy homeostasis. By mimicking adenosine monophosphate (AMP) , AICAR activates AMPK pathways, leading to increased glucose uptake, fatty acid oxidation, and mitochondrial biogenesis . This peptide has been extensively researched for its potential in enhancing endurance, promoting metabolic flexibility, and improving insulin sensitivity . Due to its ability to stimulate ATP production and optimize cellular energy metabolism , AICAR is widely studied in fields such as exercise physiology, metabolic disorders, and cardiovascular health . Potential applications of AICAR peptide research include: Increased endurance and stamina through enhanced mitochondrial efficiency Improved glucose metabolism and insulin sensitivity for metabolic regulation Enhanced fat oxidation via AMPK-driven energy expenditure Neuroprotective and cardioprotective effects linked to mitochondrial health AICAR continues to be a subject of interest in scientific research for its implications in metabolic regulation, cellular repair, and energy optimization . AICAR COA